TRANSFOG
TRANSlational and Functional Onco-Genomics
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TRANSFOG
Translational and Functional Onco-Genomics
The TRANSFOG project aims at the systematic identification and functional characterization of novel cancer genes with high potential diagnostic and therapeutic value in breast, colon and lung cancer. The TRANSFOG partner will bring together world recognised competences and resources to reach the integrated research objectives.
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Publishable Final activity report
TRANSFOG aims at the systematic identification and functional characterization of novel cancer genes with high potential diagnostic and therapeutic value. The main ambition of this project is to re-establish European leadership in the field of cancer genomics. To this aim, the project is integrating academic and industrial cutting edge groups to develop a joint effort towards systematic identification and functional characterization of novel cancer genes with high potential diagnostic and therapeutic value in breast, colon and lung cancer. The project is based on the scientific excellence of the applicants, who have made major recognized contributions to the field and on the construction of shared technological platforms.(...)
TRANSFOG brings together world-recognised competences and resources to reach the following, integrated research objectives:
1 Identification of novel cancer-related genes of high clinical-diagnostic potential, with a specific focus on progression and metastasis of colon, breast, lung cancer.
2 Set-up of technologies for systematic cancer gene functional analysis and identification of new molecular targets.
3 Systematic exploration of oncogenic/antioncogenic signalling pathways, epigenetic regulatory mechanisms to generate a comprehensive overview of the alterations in signalling and regulatory networks involved in cancer progression.
4 Development of tools for diagnostic validation of molecular signatures for cancers of high population impact, such as colon, breast and lung. This enables translation into clinical use of signatures obtained through the cancer-oriented genomic screenings performed by the Partners.
5 Establishment of a shared bioinformatic platform for functional oncogenomics data handling and standardization.
The TRANSFOG experimental pipeline consists of seven research components that synergistically enable streamlined translation of large-scale genomic screenings into highimpact contributions to cancer diagnosis and therapy. (...) read more
Scientific Coordinator : Enzo Medico
 
UPCOMING EVENT
OECI week

OECI Week (WG workshops; Scientific Conference and General Assembly) – Budapest, 16 to 18 June 2010.
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Develped and maintained by MEDINFO - DIST Updated : 27 April 2010
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