TRANSlational and Functional Onco-Genomics
Skip Navigation Links Search
Partner 3: CNIO
Partner name: Centro Nacional de Investigaciones Oncologicas
Short name: CNIO
Country: Spain
Role: CR (contractor)
The CNIO is a translational cancer research centre strongly committed to both basic and applied research with a strong focus on state-of-the-art oncogenomic research. The CNIO has a very strong expertise in the field of gene expression analysis. The Genomics Unit has an in-house microarry facility producing cDNA microarrays for both mouse and human studies. For human studies, it routinely produces and uses a chip with 13.000 spots (6500 genes) based on the Research Genetics 40.000 SV IMAGE clone collection and the 5800 MGC clones. For mouse studies, a 15.000 probe chip is in production based on the NIA 15 K cDNA clone set. Other chips can be designed according to different requirements. Moreover, the CNIO houses the Spanish National Tumour Bank Network. Therefore, the CNIO will coordinate the workpackage 1, cancer-oriented genomic screenings. Other competences of particular relevance to TRANSFOG include cancer epigenetic analysis, mouse models and bioinformatics.
Relevant Expertise
Mariano Barbacid Experimental Oncology
Miguel Angel Piris Molecular Pathology
Manel Esteller Epigenetics
Joaquin Dopazo Bioinformatics
Amancio Carnero Assay Development
  • Malumbres and Barbacid, 2001. To cycle or not to cycle: a critical decision in cancer. Nature Reviews Cancer, 1, 222-231.
  • Sotillo et al., 2001. Invasive melanoma in Cdk4 targeted mice. Proc. Natl. Acad. Sci. USA, 98, 13312-13317.
  • Sanchez-Beato et al., 2003. Cell cycle deregulation in B-cell lymphomas. Blood. 101:1220-35.
  • Esteller et al., 2002. Cancer Epigenetics and Methylation. Science, 297, 1807-8.
  • Carnero et al., 2000. Cellular immortalization: p16INK4A and p19ARF act in overlapping pathways. Nature Cell Biol 2, 148-155.
OECI week

OECI Week (WG workshops; Scientific Conference and General Assembly) – Budapest, 16 to 18 June 2010.
read more..
Develped and maintained by MEDINFO - DIST Updated : 27 April 2010
Comments on the web Comments on the contents